PCLinuxOS
PCLinuxOS is a user-friendly Linux distribution with out-of-the-box support for many popular graphics and sound cards, as well as other peripheral devices. The bootable live DVD provides an easy-to-use graphical installer and the distribution sports a wide range of popular applications for the typical desktop user, including browser plugins and full multimedia playback.
VS
Synex
Synex is a GNU/Linux distribution based on Debian's "Stable" branch, developed with the official Debian Live Build tool. It offers four separate desktop options with GNOME, LXDE, KDE Plasma and Xfce, all of which are composed of a rather frugal set of applications in its default state, without any development tools or offices suites.