Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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AV Linux
AV Linux is a versatile, Debian-based distribution featuring a large collection of audio and video production software. Additionally, it also includes a custom kernel with IRQ threading enabled for low-latency audio performance.