Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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EasyOS
EasyOS is an experimental Linux distribution which uses many of the technologies and package formats pioneered by Puppy Linux. The distribution features custom container technology called Easy Containers which can run applications or the entire desktop environment in a container.