Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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GhostBSD
GhostBSD is a user-friendly desktop operating system based on FreeBSD. Its default desktop is MATE, but a separate community edition with Xfce is available too.