Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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MocaccinoOS
MocaccinoOS is an independently-developed Linux distribution that has its origins in source-based Gentoo Linux and Sabayon Linux. It uses a custom-built package manager called "Luet", which acts as a front-end for container-based software.