Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
VS
Parrot
Parrot (formerly Parrot Security OS) is a Debian-based, security-oriented distribution featuring a collection of utilities designed for penetration testing, computer forensics, reverse engineering, hacking, privacy, anonymity and cryptography. The product, developed by Frozenbox, comes with MATE as the default desktop environment.