Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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PCLinuxOS
PCLinuxOS is a user-friendly Linux distribution with out-of-the-box support for many popular graphics and sound cards, as well as other peripheral devices. The bootable live DVD provides an easy-to-use graphical installer and the distribution sports a wide range of popular applications for the typical desktop user, including browser plugins and full multimedia playback.