Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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SmartOS
SmartOS is an open-source UNIX-like operating system based on illumos, a community fork of OpenSolaris. It features four technologies - ZFS (a combined file system and logical volume manager), DTrace (a dynamic tracing framework for troubleshooting kernel and application problems), Zones (a lightweight virtualisation solution), KVM and bhyve (two full virtualisation solutions for running a variety of guest operating systems, including Linux, Windows, BSD and Plan9).