Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
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SparkyLinux
SparkyLinux is a set of Debian-based desktop Linux distributions. The project provides separate editions with KDE Plasma, LXQt, MATE and Xfce desktops, as well as a lightweight flavour featuring the Openbox window manager.