Tails
The Amnesic Incognito Live System (Tails) is a Debian-based live DVD/USB with the goal of providing complete Internet anonymity for the user. The product ships with several Internet applications, including web browser, IRC client, mail client and instant messenger, all pre-configured with security in mind and with all traffic anonymised.
VS
Qubes OS
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.